On October 23-24, 2023, more than 80 individuals representing local and state health departments, PHIG national partners, the Centers for Disease Control and Prevention, and other public health organizations gathered in Atlanta, Georgia for the Region 4 Public Health Infrastructure Grant (PHIG) Hub Convening. This convening was hosted by the Mississippi Public Health Institute (MSPHI), which serves as the National Network of Public Health Institutes (NNPHI)’s regional hub for Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee.